Compliance with ethical standards. Guarantor: The scientific guarantor of this publication is Mehran Arab Ahmadi. Conflict of interest: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. Statistics and biometry: No complex statistical methods were necessary for this paper. Informed consent: Approval from the institutional animal care committee was not required. Ethical approval: Institutional Review Board approval was not required. Study subjects or cohorts overlap: Not applicable. Methodology: Commentary