Advanced Diagnostic & Interventional Radiology Research Center | Comparison of fetal lung maturation in fetuses with intrauterine growth restriction with control group, using lung volume, lung/liver and lung/muscle signal intensity and apparent diffusion coefficient ratios on different magnetic resonance imaging sequences

Advanced Diagnostic & Interventional Radiology Research Center | Comparison of fetal lung maturation in fetuses with intrauterine growth restriction with control group, using lung volume, lung/liver and lung/muscle signal intensity and apparent diffusion coefficient ratios on different magnetic resonance imaging sequences
| Dec 12 2025
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Advanced Diagnostic & Interventional Radiology Research Center

COVID-19 pandemic 

During the COVID-19 pandemic, the Radiology Research Center at Tehran University of Medical Sciences continued its research activities despite the challenges posed by the increased demand for CT scans of COVID-19 patients and the necessity of adhering to strict health protocols. This center played a crucial role in improving medical imaging techniques, optimizing diagnostic protocols, and advancing technologies related to CT scan image analysis.

Faculty members, researchers, and staff remained committed to ensuring the safety and well-being of healthcare professionals and patients while actively engaging in imaging data analysis, developing artificial intelligence algorithms for faster disease detection, publishing scientific articles, and presenting their findings at international conferences. These efforts aimed to enhance diagnostic accuracy, improve treatment processes, and alleviate pressure on healthcare systems.

 

Key achievements of the Radiology Research Center during the COVID-19 pandemic include:


✔️ Development and optimization of lung imaging protocols for faster and more accurate COVID-19 diagnosis
✔️ Implementation of artificial intelligence technologies for automated CT scan analysis and reduced diagnosis time
✔️ Publication of high-impact research articles on innovative imaging methods for COVID-19 patients
✔️ Participation in national and international projects focused on COVID-19 diagnosis and patient management

The center remains dedicated to advancing research in medical imaging and continues to contribute as a leading scientific institution in improving the quality of diagnostic and therapeutic services.

 

Some of the center's significant achievements during the pandemic include:

 

  • Release Date : Jul 14 2024 - 08:15
  • : 122
  • Study time : 1 minute(s)

Comparison of fetal lung maturation in fetuses with intrauterine growth restriction with control group, using lung volume, lung/liver and lung/muscle signal intensity and apparent diffusion coefficient ratios on different magnetic resonance imaging sequences

fetal lung maturation in fetuses with intrauterine growth restriction {faces}

Purpose: To compare lung volume, lung apparent diffusion coefficient (ADC) and signal intensity ratio (SIR) on different magnetic resonance imaging (MRI) sequences between intrauterine growth restriction (IUGR) fetuses and the control group.

Materials and methods: 49 IUGR and 58 non-IUGR fetuses were imaged using 3 Tesla MRI units. Total lung volume (TLV), lung/liver SIR (LLSIR) and lung/muscle SIR (LMSIR) in T1 and T2-weighted sequences and lung/liver ADC ratio (LLADCR) and lung/muscle ADC ratio (LMADCR) were assessed.

Results: LLSIR and LMSIR were significantly higher in the T1-weighted sequence (p-value: .03) and LLADCR and LMADCR were significantly lower on diffusion-weighted imaging (DWI) in IUGR fetuses compared to the control group (p-value: .01). There was no significant difference in SIRs in the T2-weighted sequence between the two groups. Although TLV was increased with gestational age in both groups, it was significantly lower in the IUGR group (mean: 82 ± 22.7 ml vs. 110.8 ± 18 ml, p-value: <.001).

Conclusion: The T1-weighted sequence and DWI seem to be better than the T2-weighted sequence for assessing the faint difference of lung maturity between groups. However, SIR differences were not as meaningful as TLV differences and this could be related to the complex maturation process in IUGR fetuses as the effect of higher endogenous corticosteroids

  • Article_DOI : 10.1080/14767058.2021.2008349
  • Author(s) : behnaz moradi ,mahboobeh shirazi,zohre ghorbani
  • News Group : research,research article
  • News Code : 277971
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