Advanced Diagnostic & Interventional Radiology Research Center | Evaluation of Ethanol Injection, Radiofrequency Ablation, and Levothyroxine Therapy in the Management of Benign Thyroid Nodules

COVID-19 pandemic

During the COVID-19 pandemic, the Radiology Research Center at Tehran University of Medical Sciences continued its research activities despite the challenges posed by the increased demand for CT scans of COVID-19 patients and the necessity of adhering to strict health protocols. This center played a crucial role in improving medical imaging techniques, optimizing diagnostic protocols, and advancing technologies related to CT scan image analysis.

Faculty members, researchers, and staff remained committed to ensuring the safety and well-being of healthcare professionals and patients while actively engaging in imaging data analysis, developing artificial intelligence algorithms for faster disease detection, publishing scientific articles, and presenting their findings at international conferences. These efforts aimed to enhance diagnostic accuracy, improve treatment processes, and alleviate pressure on healthcare systems.

Key achievements of the Radiology Research Center during the COVID-19 pandemic include:

✔️ Development and optimization of lung imaging protocols for faster and more accurate COVID-19 diagnosis
✔️ Implementation of artificial intelligence technologies for automated CT scan analysis and reduced diagnosis time
✔️ Publication of high-impact research articles on innovative imaging methods for COVID-19 patients
✔️ Participation in national and international projects focused on COVID-19 diagnosis and patient management

The center remains dedicated to advancing research in medical imaging and continues to contribute as a leading scientific institution in improving the quality of diagnostic and therapeutic services.

Evaluation of Ethanol Injection, Radiofrequency Ablation, and Levothyroxine Therapy in the Management of Benign Thyroid Nodules

Ethanol, Rf Ablation, Levothyroxine in the of Benign Thyroid Nodules {faces}

Background:

Thyroid nodules are common clinical findings. Although there are various accepted treatments for benign thyroid nodules, such as surgery and thermal treatment, there are some alternative methods for the management of these patients at lower costs with minimal complications.

Objectives:

This study aimed to compare volume reduction in radiofrequency (RF) ablation and single-session ethanol ablation (EA) and to investigate the effects of levothyroxine therapy (LT4) on benign thyroid nodules.

Patients and Methods:

In this clinical trial, 91 patients with benign thyroid nodules, presenting to different medical centers in Tehran, Iran, from December 6, 2018, to December 6, 2019, were included. Patients who met the inclusion criteria were selected and randomly allocated into three groups: group 1, a single session of RF ablation (n = 31); group 2, a single session of ethanol injection (n = 30); and group 3, a six-month LT4 treatment (n = 30). Thyroid tests, including thyroid stimulating hormone (TSH), thyroxine (T4), triiodothyronine (T3), anti-thyroid peroxidase (anti-TPO), T3 resin uptake (T3RU), and serum calcitonin level, were recorded at baseline and within one-, three-, and six-month intervals. The nodule volume was also assessed using sonography at baseline and in the follow-ups.

Results:

The mean volume reduction was 73.6%, 80.1%, and 8.7% at six months after the intervention in the ethanol injection, RF ablation, and LT4 treatment groups, respectively (P < 0.001). There was a significant relationship between the mean volume reduction and the follow-up period (one, three, and six months) (P < 0.001).

Conclusion:

The RF ablation therapy was found to be the optimal modality for the management of benign thyroid nodules, as it was associated with the greatest mean volume reduction. Conversely, the lowest mean volume reduction was observed in the LT4 treatment group during six months of follow-up

Article_DOI :
Author(s) :
News Group : research,articles,research article
News Code : 277909

Change font color:

Main Color:

Secondary Color:

Change Background Color:

Change font size:

Change word space:

Change line space:

Change mouse pointer:

Change font

Choose blind mode

By selecting the color blind mode, the images of this website will be optimized according to your color blind mode

red blindness green blindness blue blindness Red difficult to see greendifficult to see blue difficult to see monochrome nose Monochrome conical nose

Advanced Diagnostic & Interventional Radiology Research Center | Evaluation of Ethanol Injection, Radiofrequency Ablation, and Levothyroxine Therapy in the Management of Benign Thyroid Nodules

Advanced Diagnostic & Interventional Radiology Research Center

COVID-19 pandemic

Key achievements of the Radiology Research Center during the COVID-19 pandemic include:

Some of the center's significant achievements during the pandemic include: