Advanced Diagnostic & Interventional Radiology Research Center | Evaluation of Suspicious Appearing Microcalcification Groups on

COVID-19 pandemic

During the COVID-19 pandemic, the Radiology Research Center at Tehran University of Medical Sciences continued its research activities despite the challenges posed by the increased demand for CT scans of COVID-19 patients and the necessity of adhering to strict health protocols. This center played a crucial role in improving medical imaging techniques, optimizing diagnostic protocols, and advancing technologies related to CT scan image analysis.

Faculty members, researchers, and staff remained committed to ensuring the safety and well-being of healthcare professionals and patients while actively engaging in imaging data analysis, developing artificial intelligence algorithms for faster disease detection, publishing scientific articles, and presenting their findings at international conferences. These efforts aimed to enhance diagnostic accuracy, improve treatment processes, and alleviate pressure on healthcare systems.

Key achievements of the Radiology Research Center during the COVID-19 pandemic include:

✔️ Development and optimization of lung imaging protocols for faster and more accurate COVID-19 diagnosis
✔️ Implementation of artificial intelligence technologies for automated CT scan analysis and reduced diagnosis time
✔️ Publication of high-impact research articles on innovative imaging methods for COVID-19 patients
✔️ Participation in national and international projects focused on COVID-19 diagnosis and patient management

The center remains dedicated to advancing research in medical imaging and continues to contribute as a leading scientific institution in improving the quality of diagnostic and therapeutic services.

Evaluation of Suspicious Appearing Microcalcification Groups on Mammogram: Comparing BI-RADS 5th Edition Descriptors with the BI-RADS 4th Edition and Pathologic Association

Suspicious Appearing Microcalcification Groups on Mammogram {faces}

Background:

Groups of microcalcifications are the most frequent recognized features of ductal carcinoma on mammograms. However, heterogeneity (in size, morphology and density) and number of microcalcification groups as well as presence of accompanied soft-tissue density are not included in breast imaging reporting and data system (BI-RADS) descriptors.

Objectives:

The study purposes to determine the malignancy risk of microcalcification groups regarding these characteristics and also compare the 4th and 5th versions of BI-RADS.

Patients and Methods:

In a cross sectional study, 88 patients with microcalcification groups (age range, 26 - 80 years; mean, 53.4 years) who had undergone mammographically guided biopsy between March 2013 and March 2015 were evaluated. The overall number of microcalcification groups in each patient, number of deposits within each group, group location and heterogeneity in size, density and morphology were assessed and subsequently BI-RADS descriptors for 4th and 5th editions were recorded separately. Finally, correlation with histopathology was performed.

Results:

Overall, positive predictive value (PPV) of suspicious microcalcifications was 22.4%. PPVs of morphology descriptors were as follows: amorphous, 7.9%; coarse heterogeneous, 17.8%; fine pleomorphic, 63.2%; fine linear/fine linear branching, 100%; (P < 0.001). Heterogenicity in size existed in 81 cases (92%), in density in 69 cases (86.4%) and in morphology in 86 cases (97.7%). Additionally, microcalcification groups that were accompanied with soft-tissue density had a higher percentage of malignancy (67.5% vs. 54.5%) but with no significant difference (P = 0.2). According to BI-RADS 4th edition, the risk of malignancy was 49.1%, 66.7% and 88.1% in 4b, 4c and 5, respectively. These figures were 30%, 82.9%, and 100% for BI-RADS 5th version, respectively. The area under the receiver (AUC) of 4th and 5th versions of BI-RADS was 0.76 and 0.74 (both P values < 0.001, 95% confidence intervals = 0.66-0.87 and 0.63 - 0.85 respectively). P value for comparison was insignificant.

Conclusion:

The risk of malignancy increased with the heterogeneity of microcalcifications, especially in the groups with heterogeneity in density, however with no statistically significant difference. BI-RADS 5th edition could predict the likelihood of malignancy as well as 4th version

Article_DOI : doi.org/10.5812/iranjradiol.14013
Author(s) : nasrin ahmadinejad,maryam jafari
News Group : research,research article
News Code : 278382

bi-rads_

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Advanced Diagnostic & Interventional Radiology Research Center | Evaluation of Suspicious Appearing Microcalcification Groups on

Advanced Diagnostic & Interventional Radiology Research Center

COVID-19 pandemic

Key achievements of the Radiology Research Center during the COVID-19 pandemic include:

Some of the center's significant achievements during the pandemic include: