Multimodal MRI Techniques and Their Importance in Frameless Navigation Biopsy for Brain Glioma

Gliomas represent 86% of primary intracranial malig-
nant tumors. Their most malignant form, glioblastoma
multiform (GBM), is either astrocytic, oligodendrocytic,
or includes a variety of other histo-pathological subtypes
. The best non-invasive imaging modality for neuro-
oncologic evaluation of the patients is MRI, which is used
for differential diagnosis, biopsy guidance, therapeutic
planning, and follow-up